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Is Alzheimer’s contagious?

Scientists have suggested that in some instances, an infection might contribute to the development of Alzheimer’s, and the disease may even be contagious.


This computer graphic contrasts an Alzheimer’s-affected brain (left) with a healthy brain, illustrating its shrinkage due to the degeneration and death of nerve cells.

The brain damage associated with this neurological condition resembles that resulting from infectious diseases, such as mad cow disease and the human variant, CJD.

In experiments conducted on mice, researchers discovered that the condition arises when a normal protein misfolds, subsequently spreading by converting ‘good’ proteins into ‘bad’ ones. This mechanism is also observed in mad cow disease and CJD.

Being the most prevalent form of dementia, this degenerative condition impacts millions of individuals worldwide.

It is estimated that one in 14 individuals over the age of 65 is affected by it.

In certain cases, the condition can be inherited.

A notable figure diagnosed with the disease is author Terry Pratchett.

The condition results from the deterioration of specific brain regions, particularly within the cerebral cortex.
As the grey matter diminishes, clusters of protein, referred to as ‘plaques’ and ‘tangles,’ begin to accumulate in the brain, leading to further destruction of brain cells.

Initial symptoms may involve minor memory issues and difficulty finding the correct words.

As the disease progresses, more severe symptoms manifest, including significant confusion and pronounced personality changes. Affected individuals may also experience delusions.

While there is currently no cure, some treatments exist that can slow the advancement of the disease.

The condition has the potential to reduce life expectancy, as sufferers may lose interest in eating and personal hygiene, which can result in additional health complications.

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